(S)-(-)-BINAP CAS 76189-56-5 Purity ≥99.0% (HPLC) E.E ≥99.0% Factory

(S)-(-)-BINAP (CAS: 76189-56-5), is an organic phosphine compound and is useful as a chiral catalyst and pharmaceutical intermediate. Chiral ligand for metal mediated asymmetric catalysis.
2,2′-Bis(diphenylphosphino)-1,1′-Binaphthyl and its rhodium and ruthenium derivatives can be used as highly selective homogeneous catalysts for the reduction of aryl ketones, β-ketoesters and α-aminoketones. It can also be used in asymmetric hydrogenation and hydroformylation reactions of olefins, asymmetric Heck reactions and asymmetric isomerization reactions of allyl groups.
Reaction
Ligand employed in palladium-catalyzed asymmetric arylation of ketones.
Ligand employed in rhodium-catalyzed 1,4-additions to enones.
Ligand employed in palladium-catalyzed hydroamination of styrene derivatives.
Ligand employed in silver-catalyzed asymmetric Sakuri-Hosomi allylation and Mukaiyama aldol reaction.
Ligand employed in rhodium-catalyzed kinetic resolution of enynes.
Ligand employed in asymmetric rhodium-catalyzed hydroboration of cyclopropenes.
Ligand employed in silver-catalyzed a-hydroxylation of stannyl enol ethers.
Ligand employed in palladium-catalyzed synthesis of chiral allenes.
Uses Reactant involved in:
Enantioselective and diastereoselective unpoled carbonyl allylation
Syntehsis of organophophine oxides as anittumor agents
SN2 halogenation of hydroxy groups
Synthesis of BINAP complexes
Studies of conformational flexibility of BINAP chelates